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Anti-Troponin T Antibody (Monoclonal, JLT-12)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IHC-F |
|---|---|
| Primary Accession | P09739 |
| Host | Mouse |
| Isotype | Mouse IgG1 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Format | Lyophilized |
| Description | Mouse IgG monoclonal antibody for Troponin T, troponin T type 1 (skeletal, slow); troponin T type 2 (cardiac); troponin T type 3 (skeletal, fast) (TNNT1; TNNT2; TNNT3) detection. Tested with WB, IHC-P, IHC-F in Rat;rabbit;chicken. No cross reactivity with other proteins. |
| Reconstitution | Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
| Gene ID | 24838 |
|---|---|
| Other Names | Troponin T, fast skeletal muscle, TnTf, Fast skeletal muscle troponin T, fTnT, Tnnt3 |
| Calculated MW | 30750 MW KDa |
| Application Details | Immunohistochemistry(Paraffin-embedded Section), 4-8 µg/ml, Rat, rabbit, chicken, By Heat Immunohistochemistry(Frozen Section), 4-8 µg/ml, Rat, rabbit, chicken, - Western blot, 2-4 µg/ml, Rat, rabbit, chicken |
| Protein Name | Troponin T, slow skeletal muscle; Troponin T, cardiac muscle; Troponin T, fast skeletal muscle |
| Contents | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
| Clone Names | JLT-12 |
| Immunogen | Troponin T from rabbit skeletal muscle. |
| Purification | Ascites |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the troponin T family. |
| Name | Tnnt3 |
|---|---|
| Function | Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The troponin complex is located on the thin filament of striated muscle and is composed of 3 component polypeptides: troponin 1, troponin T and troponin C. Three troponin T genes have been described on the basis of molecular cloning in humans and other vertebrates. These are expressed in a tissue-specific manner and encode the troponin T isoforms expressed in slow skeletal muscle(TNNT1), cardiac muscle(TNNT2),and fast skeletal muscle(TNNT3). TNNT1, TNNT2, TNNT3 are located on 19q13.4, 1q32, 11p15.5 respectively.
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