Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.ELITE™ Monoclonal Antibody Services
Abcepta is a leading manufacturer of off the shelf and custom antibodies with over 20,000 antibodies developed over the last decade. Our ELITE Monoclonal Antibody Custom Service* is ideal for projects requiring high specificity and a low background. Monoclonal antibodies are highly homogenous and allow for unlimited production with sustained specificity.
We offer primary Monoclonal Antibody Service in Balb/c mice, as well as antibody characterization, validation optimization, and scale up. Our highly experienced team can develop a pre-optimized antibody validated in the assay of your choosing. Please contact us to learn more about these and other service offerings.
| Services | Days |
|
Peptide antigen design and preparation: Peptide synthesis of up to 18 AA residues with purity > 95% Peptide conjugation to KLH carrier protein OR Recombinant protein（offered by customer, >95% pure by SDS Page) |
14 7 7 |
|
One primary intramuscular injection of 50 ug conjugated peptide/protein with adjuvant per mouse
One intramuscular injection of 50 ug conjugated peptide/protein with adjuvant per mouse Bleed from tail tips on day 21 post-priming and measure antibody titers by ELISA. Hybridoma fusion from mouse with best titer, positive antigen screen by ELISA of growing clones, followed by 2 rounds subcloning for selected clones including subtype identification and clone amplification |
63 |
|
1 L culture for expression and Protein G purification for one clone. Typical yield of 10-30 mg purified antibody plus hybridoma for delivery to customer |
14 7 |
| Optional: Application Validation Test WB, IHC, IF, FC | 3 |
| Total: | ~94-108 |
How It Works:
An experienced custom services project manager will reply to your request with a quotation by email. A teleconference to review project scope and deliverables may also be arranged at client request.
Once you approve the quote, send it as an attachment with your purchase order to sales@abcepta.com You will receive a confirmation of the order and project updates at regular intervals during the production.
Order Information:
Email:
USA: sales@abcepta.com
Phone:
USA: 888.735.7227 (toll free) or 858.875.1900
Fax:
USA: 858-875-1999
For additional information visit :
ELITE Custom Antibody Service Brochure