ApoSAA Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P0DJI8 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 13546 Da |
Gene ID | 6288 |
---|---|
Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Recombinant human Apo-SAA can be used as a positive control. The antibody recognizes ~13 kDa recombinant human Apo-SAA. Reactivity to other species has not been tested. |
Other Names | apo-lipoprotein, apolipoprotein, apolipoprotein-SAA, apolipoproteinSAA, apolipoprotein SAA, apo-SAA, apoSAA, apo SAA |
Target/Specificity | ApoSAA |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 0.5% BSA, 30% glycerol and 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | ApoSAA Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SAA1 |
---|---|
Function | Major acute phase protein. |
Cellular Location | Secreted. |
Tissue Location | Expressed by the liver; secreted in plasma (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Human apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 µg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apo-lipoprotein. The human SAA gene codes for a 122 amino acid polypeptide, which contains an 18 amino acid N-terminal signal sequence.
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