DUSP14 / MKP6 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC, E |
---|---|
Primary Accession | O95147 |
Other Accession | NP_008957.1, 11072, 56405 (mouse) |
Predicted | Human, Mouse, Rat, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 22255 Da |
Gene ID | 11072 |
---|---|
Other Names | Dual specificity protein phosphatase 14, 3.1.3.16, 3.1.3.48, MKP-1-like protein tyrosine phosphatase, MKP-L, Mitogen-activated protein kinase phosphatase 6, MAP kinase phosphatase 6, MKP-6, DUSP14, MKP6 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DUSP14 / MKP6 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DUSP14 |
---|---|
Synonyms | MKP6 |
Function | Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases. Plays a negative role in TCR signaling by dephosphorylating MAP3K7 adapter TAB1 leading to its inactivation (PubMed:24403530). |
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Provided below are standard protocols that you may find useful for product applications.
References
Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6. Marti F, Krause A, Post NH, Lyddane C, Dupont B, Sadelain M, King PD. J Immunol. 2001 Jan 1;166(1):197-206. PMID: 11123293
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