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ELF5 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q9UKW6 |
| Other Accession | NP_938195.1, NP_001413.1, 2001, 13711 (mouse) |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 31263 Da |
| Gene ID | 2001 |
|---|---|
| Other Names | ETS-related transcription factor Elf-5, E74-like factor 5, Epithelium-restricted ESE-1-related Ets factor, Epithelium-specific Ets transcription factor 2, ESE-2, ELF5, ESE2 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ELF5 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ELF5 |
|---|---|
| Synonyms | ESE2 |
| Function | Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}. |
| Tissue Location | Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tissues. In the kidney, only isoform 1 was expressed, while prostate expressed both isoforms, with levels of isoform 2 being higher Expression is up-regulated during keratinocyte differentiation. Several epithelial carcinoma cell lines showed lack of expression |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognise both reported Human isoforms represented by NP_938195.1 and NP_001413.1.
References
Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes. Oettgen P, Kas K, Dube A, Gu X, Grall F, Thamrongsak U, Akbarali Y, Finger
E, Boltax J, Endress G, Munger K, Kunsch C, Libermann TA. J Biol Chem. 1999 Oct 8;274(41):29439-52. PMID: 10506207
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