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FOXI3 / Forkhead box I3 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC, E |
|---|---|
| Primary Accession | A8MTJ6 |
| Other Accession | NP_001129121.1, 344167 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 43326 Da |
| Gene ID | 344167 |
|---|---|
| Other Names | Forkhead box protein I3, FOXI3 |
| Dilution | IHC~~1:100~500 E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FOXI3 / Forkhead box I3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FOXI3 {ECO:0000303|PubMed:36260083, ECO:0000312|HGNC:HGNC:35123} |
|---|---|
| Function | Transcription factor required for pharyngeal arch development, which is involved in hair, ear, jaw and dental development (PubMed:37041148). May act as a pioneer transcription factor during pharyngeal arch development (By similarity). Required for epithelial cell differentiation within the epidermis (By similarity). Acts at multiple stages of otic placode induction: necessary for preplacodal ectoderm to execute an inner ear program (By similarity). Required for hair follicle stem cell specification (By similarity). Acts downstream of TBX1 for the formation of the thymus and parathyroid glands from the third pharyngeal pouch (By similarity). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Expression of mouse Foxi class genes in early craniofacial development. Ohyama T, Groves AK. Dev Dyn. 2004 Nov;231(3):640-6. PMID: 15376323
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