|Application ||WB, E|
|Other Accession||NP_005919.2, NP_001108086.1, 4240|
|Calculated MW||43105 Da|
|Other Names||Lactadherin, Breast epithelial antigen BA46, HMFG, MFGM, Milk fat globule-EGF factor 8, MFG-E8, SED1, Lactadherin short form, Medin, MFGE8|
|Immunogen||This antibody is expected to recognize both reported isoforms (NP_005919.2; NP_001108086.1).|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Lactadherin Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction.|
|Cellular Location||Membrane; Peripheral membrane protein. Secreted|
|Tissue Location||Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas|
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