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Goat Anti-Lactadherin Antibody (internal region)
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Application 
| WB, E |
|---|---|
| Primary Accession | Q08431 |
| Other Accession | NP_005919.2, NP_001108086.1, 4240 |
| Reactivity | Human |
| Predicted | Human |
| Host | Goat |
| Isotype | IgG |
| Calculated MW | 43105 Da |
| Gene ID | 4240 |
|---|---|
| Other Names | Lactadherin, Breast epithelial antigen BA46, HMFG, MFGM, Milk fat globule-EGF factor 8, MFG-E8, SED1, Lactadherin short form, Medin, MFGE8 |
| Immunogen | This antibody is expected to recognize both reported isoforms (NP_005919.2; NP_001108086.1). |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-Lactadherin Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MFGE8 |
|---|---|
| Function | Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. |
| Cellular Location | Membrane; Peripheral membrane protein. Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:P79385}; Peripheral membrane protein {ECO:0000250|UniProtKB:P79385}. Note=Located in the acrosomal region of zona-pellucida bound sperm. {ECO:0000250|UniProtKB:P79385} |
| Tissue Location | Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas |
Research Areas
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Application Protocols
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$ 341.00
Cat# AF4300a
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