Goat anti-Heme Oxygenase 1 (aa242-256) Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, Pep-ELISA |
|---|---|
| Primary Accession | P09601 |
| Other Accession | NP_002124.1 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | HMOX1 |
| Calculated MW | 32819 Da |
| Gene ID | 3162 |
|---|---|
| Other Names | HMOX1; heme oxygenase (decycling) 1; HO-1; HSP32; bK286B10; OTTHUMP00000198812; heat shock protein, 32-kD; heme oxygenase 1 |
| Dilution | WB~~1:1000 Pep-ELISA~~N/A |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-Heme Oxygenase 1 (aa242-256) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HMOX1 |
|---|---|
| Synonyms | HO, HO1 |
| Function | [Heme oxygenase 1]: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron (PubMed:11121422, PubMed:19556236, PubMed:7703255). Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis (PubMed:20055707). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side |
| Tissue Location | Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level) |

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