|Other Accession||NM_001052, NP_001043|
|Alias Symbol||SS4R, SS4-R, SS-4-R|
|Other Names||Somatostatin receptor type 4, SS-4-R, SS4-R, SS4R, SSTR4|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-SSTR4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SSTR4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals|
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Provided below are standard protocols that you may find useful for product applications.
Pasquali,D., et al., (2002) J. Clin. Endocrinol. Metab. 87 (11), 5125-5129Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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