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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Pax8 antibody - C-terminal region   

Pax8 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Pax8 antibody - C-terminal region AI10616
    WB Suggested Anti-Pax8 Antibody
    Titration: 1. μg/ml
    Positive Control: Mouse Pancreas
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q00288
Other Accession NM_011040, NP_035170
Reactivity Human, Mouse, Rat, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 49kDa
Additional Information
Alias Symbol Pax-8
Other Names Paired box protein Pax-8, Pax8, Pax-8
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Pax8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPax8 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pax8
Synonyms Pax-8
Function Thought to encode a transcription factor. It may have a role in kidney cell differentiation. May play a regulatory role in mammalian development.
Cellular Location Nucleus.
Tissue Location Expressed in the developing excretory system and the thyroid gland EMBL; X57487; CAA40725.1; -; mRNA EMBL; X99592; CAA67904.1; -; Genomic_DNA EMBL; X99593; CAA67904.1; JOINED; Genomic_DNA EMBL; X99594; CAA67904.1; JOINED; Genomic_DNA EMBL; X99595; CAA67904.1; JOINED; Genomic_DNA EMBL; X99596; CAA67904.1; JOINED; Genomic_DNA EMBL; X99597; CAA67904.1; JOINED; Genomic_DNA EMBL; X99598; CAA67904.1; JOINED; Genomic_DNA EMBL; AL732528; CAM17808.1; -; Genomic_DNA EMBL; CH466542; EDL08172.1; -; Genomic_DNA EMBL; BC020526; AAH20526.1; -; mRNA CCDS; CCDS15738.1; - PIR; A56925; A56925 RefSeq; NP_035170.1; NM_011040.4 UniGene; Mm.2533; - ProteinModelPortal; Q00288; - SMR; Q00288; - BioGrid; 202035; 2 IntAct; Q00288; 1 STRING; 10090.ENSMUSP00000028355; - iPTMnet; Q00288; - PhosphoSitePlus; Q00288; - MaxQB; Q00288; - PaxDb; Q00288; - PRIDE; Q00288; - Ensembl; ENSMUST00000028355; ENSMUSP00000028355; ENSMUSG00000026976 GeneID; 18510; - KEGG; mmu:18510; - UCSC; uc008ipb.2; mouse CTD; 7849; - MGI; MGI:97492; Pax8 eggNOG; KOG3862; Eukaryota eggNOG; ENOG410ZT0S; LUCA GeneTree; ENSGT00940000161868; - HOGENOM; HOG000230938; - HOVERGEN; HBG009115; - InParanoid; Q00288; - KO; K09293; - OrthoDB; 592933at2759; - TreeFam; TF315397; - PRO; PR:Q00288; - Proteomes; UP000000589; Chromosome 2 Bgee; ENSMUSG00000026976; Expressed in 125 organ(s), highest expression level in early tubule (mouse) ExpressionAtlas; Q00288; baseline and differential Genevisible; Q00288; MM GO; GO:0005654; C:nucleoplasm; ISS:UniProtKB GO; GO:0005634; C:nucleus; IDA:MGI GO; GO:0005667; C:transcription factor complex; TAS:MGI GO; GO:0003677; F:DNA binding; ISS:UniProtKB GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; ISO:MGI GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:UniProtKB GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; ISS:UniProtKB GO; GO:0043565; F:sequence-specific DNA binding; ISO:MGI GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB GO; GO:0009887; P:animal organ morphogenesis; TAS:MGI GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl GO; GO:0030154; P:cell differentiation; IMP:MGI GO; GO:0071371; P:cellular response to gonadotropin stimulus; ISO:MGI GO; GO:0007417; P:central nervous system development; IEP:UniProtKB GO; GO:0042472; P:inner ear morphogenesis; IGI:UniProtKB GO; GO:0072073; P:kidney epithelium development; IEP:UniProtKB GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl GO; GO:0072164; P:mesonephric tubule development; IEP:UniProtKB GO; GO:0001823; P:mesonephros development; IMP:UniProtKB GO; GO:0072278; P:metanephric comma-shaped body morphogenesis; IEA:Ensembl GO; GO:0072221; P:metanephric distal convoluted tubule development; IMP:UniProtKB GO; GO:0072289; P:metanephric nephron tubule formation; IMP:UniProtKB GO; GO:0072284; P:metanephric S-shaped body morphogenesis; IEA:Ensembl GO; GO:0001656; P:metanephros development; IGI:MGI GO; GO:1900215; P:negative regulation of apoptotic process involved in metanephric collecting duct development; IMP:UniProtKB GO; GO:1900218; P:negative regulation of apoptotic process involved in metanephric nephron tubule development; IMP:UniProtKB GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:BHF-UCL GO; GO:0072305; P:negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis; IMP:UniProtKB GO; GO:1900212; P:negative regulation of mesenchymal cell apoptotic process involved in metanephros development; IMP:UniProtKB GO; GO:0071599; P:otic vesicle development; IEA:Ensembl GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IMP:UniProtKB GO; GO:0072108; P:positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; IMP:UniProtKB GO; GO:2000594; P:positive regulation of metanephric DCT cell differentiation; IMP:UniProtKB GO; GO:2000611; P:positive regulation of thyroid hormone generation; IMP:UniProtKB GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISO:MGI GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB GO; GO:0039003; P:pronephric field specification; IEP:UniProtKB GO; GO:0048793; P:pronephros development; IMP:UniProtKB GO; GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB GO; GO:0072307; P:regulation of metanephric nephron tubule epithelial cell differentiation; IMP:UniProtKB GO; GO:2000612; P:regulation of thyroid-stimulating hormone secretion; ISS:UniProtKB GO; GO:0006355; P:regulation of transcription, DNA-templated; ISO:MGI GO; GO:0072050; P:S-shaped body morphogenesis; IEP:UniProtKB GO; GO:0006790; P:sulfur compound metabolic process; IEA:Ensembl GO; GO:0030878; P:thyroid gland development; IMP:MGI GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB GO; GO:0001655; P:urogenital system development; IGI:UniProtKB GO; GO:0003281; P:ventricular septum development; IMP:BHF-UCL CDD; cd00131; PAX; 1 Gene3D;; -; 2 InterPro; IPR009057; Homeobox-like_sf InterPro; IPR001523; Paired_dom InterPro; IPR022130; Pax2_C InterPro; IPR036388; WH-like_DNA-bd_sf Pfam; PF00292; PAX; 1 Pfam; PF12403; Pax2_C; 1 PRINTS; PR00027; PAIREDBOX SMART; SM00351; PAX; 1 SUPFAM; SSF46689; SSF46689; 1 PROSITE; PS00034; PAIRED_1; 1 PROSITE; PS51057; PAIRED_2; 1 1: Evidence at protein level; Complete proteome; Developmental protein; Differentiation; DNA-binding; Nucleus; Paired box; Phosphoprotein; Reference proteome; Transcription; Transcription regulation CHAIN 1 457 Paired box protein Pax-8 /FTId=PRO_0000050198 DOMAIN 9 135 Paired. {ECO:0000255|PROSITE- ProRule:PRU00381} COMPBIAS 316 328 Ser-rich MOD_RES 304 304 Phosphoserine CONFLICT 340 340 G -> D (in Ref. 2; no nucleotide entry) SEQUENCE 457 AA; 48793 MW; AAACD3EE54AA4488 CRC64; MPHNSIRSGH GGLNQLGGAF VNGRPLPEVV RQRIVDLAHQ GVRPCDISRQ LRVSHGCVSK ILGRYYETGS IRPGVIGGSK PKVATPKVVE KIGDYKRQNP TMFAWEIRDR LLAEGVCDND TVPSVSSINR IIRTKVQQPF NLPMDSCVAT KSLSPGHTLI PSSAVTPPES PQSDSLGSTY SINGLLGIAQ PGNDNKRKMD DSDQDSCRLS IDSQSSSSGP RKHLRTDTFS QHHLEALECP FERQHYPEAY ASPSHTKGEQ GLYPLPLLNS ALDDGKATLT SSNTPLGRNL STHQTYPVVA DPHSPFAIKQ ETPELSSSSS TPSSLSSSAF LDLQQVGSGG PAGASVPPFN AFPHAASVYG QFTGQALLSG REMVGPTLPG YPPHIPTSGQ GSYASSAIAG MVAGSEYSGN AYSHTPYSSY SEAWRFPNSS LLSSPYYYSS TSRPSAPPTS ATAFDHL
Research Areas
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$ 295.00
Cat# AI10616
Availability: 2-3 days
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