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CNN2 Antibody
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q99439 |
| Reactivity | Human, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 34kDa |
| Dilution | ELISA (1:32000), IHC-P (2.5-3.75 µg/ml), WB (0.03-0.1 µg/ml) |
| Gene ID | 1265 |
|---|---|
| Other Names | Calponin-2, Calponin H2, smooth muscle, Neutral calponin, CNN2 |
| Target/Specificity | Human CNN2. This antibody is expected to recognize both reported isoforms (NP_004359.1; NP_958434.1), but it is not expected to cross-react with CCN3. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | CNN2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CNN2 |
|---|---|
| Function | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
| Tissue Location | Heart and smooth muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
References
Masuda H.,et al.J. Biochem. 120:415-424(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Kuromitsu J.,et al.Mol. Cell. Biol. 17:707-712(1997).
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