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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-SEPT8 / Septin 8 Antibody (clone 1G3-7D1)
Anti-SEPT8 / Septin 8 Antibody (clone 1G3-7D1)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q92599 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1,k |
| Clone Names | 1G3-7D1 |
| Calculated MW | 55756 Da |
| Dilution | ELISA, IHC-P (3 - 5 µg/ml), WB |
| Gene ID | 23176 |
|---|---|
| Alias Symbol | SEPT8 |
| Other Names | SEPT8, KIAA0202, SEP2, Septin-8, Septin 8 |
| Target/Specificity | Human SEPT8 |
| Reconstitution & Storage | Protein A purified |
| Precautions | Anti-SEPT8 / Septin 8 Antibody (clone 1G3-7D1) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SEPTIN8 (HGNC:16511) |
|---|---|
| Function | Filament-forming cytoskeletal GTPase (By similarity). May play a role in platelet secretion (PubMed:15116257). Seems to participate in the process of SNARE complex formation in synaptic vesicles (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:B0BNF1}. Cytoplasm, cytoskeleton. Synapse {ECO:0000250|UniProtKB:B0BNF1}. Cell projection, axon {ECO:0000250|UniProtKB:B0BNF1}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:B0BNF1}. Presynapse {ECO:0000250|UniProtKB:B0BNF1}. Note=Expressed in axons of immature neurons, localizes to synapses in mature neurons (By similarity). In platelets, found in areas surrounding alpha-granules (PubMed:15116257) {ECO:0000250|UniProtKB:B0BNF1, ECO:0000269|PubMed:15116257} |
| Tissue Location | Widely expressed, including in brain, heart and platelets; most abundant in aorta. Isoform 2 is expressed at low levels in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 1 and 3 are highly expressed in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 2 is highly expressed in prostate, testis and ovary Isoform 1 and isoform 3 are expressed at low levels in prostate, testis and ovary. |
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