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Anti-E4F1 / E4F Antibody (clone 4B10)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q66K89 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a,k |
| Clone Names | 4B10 |
| Calculated MW | 83496 Da |
| Dilution | ELISA, IF (10 µg/ml), IHC-P (5 µg/ml), WB |
| Gene ID | 1877 |
|---|---|
| Alias Symbol | E4F1 |
| Other Names | E4F1, E4F, E4F transcription factor 1, p50E4F, Transcription factor E4F1, Transcription factor E4F, p120E4F, p120e4f transcription factor |
| Target/Specificity | Human E4F1 / E4F |
| Reconstitution & Storage | Protein A purified |
| Precautions | Anti-E4F1 / E4F Antibody (clone 4B10) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | E4F1 |
|---|---|
| Synonyms | E4F |
| Function | May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin- associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription. |
| Cellular Location | Nucleus, nucleoplasm. Cytoplasm. Note=A small fraction is detected in the cytoplasm. Excluded from the nucleolus where it is targeted upon CDKN2A overexpression. Localizes to the mitotic spindle during embryogenesis. |
| Tissue Location | Ubiquitously expressed. |
Research Areas
Citations (0)
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Application Protocols
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