Anti-ADH7 Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P40394 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 41481 Da |
Dilution | ELISA, IHC-P (10 µg/ml), WB |
Gene ID | 131 |
---|---|
Alias Symbol | ADH7 |
Other Names | ADH7, Alcohol dehydrogenase VII, ADH-4, Alcohol dehydrogenase-7, Gastric alcohol dehydrogenase, Retinol dehydrogenase |
Target/Specificity | Human ADH7 |
Reconstitution & Storage | Caprylic acid and ammonium sulfate precipitation |
Precautions | Anti-ADH7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADH7 (HGNC:256) |
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Function | Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives (PubMed:15369820, PubMed:16787387, PubMed:9600267). Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis- retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid (PubMed:15369820, PubMed:16787387, PubMed:9600267). In vitro can also catalyzes the NADH-dependent reduction of all-trans- retinal and aldehydes and their derivatives (PubMed:15369820, PubMed:16787387, PubMed:9600267). Reduces preferentially all trans- retinal, all-trans-4-oxoretinal and hexanal (PubMed:15369820, PubMed:16787387). Catalyzes in the oxidative direction with higher efficiency (PubMed:16787387, PubMed:15369820). Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation (PubMed:9600267, PubMed:15369820, PubMed:16787387). |
Cellular Location | Cytoplasm. |
Tissue Location | Preferentially expressed in stomach. |
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