Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   DLG4 Antibody (C-term) (Rat) (Ascites)   

DLG4 Antibody (C-term) (Rat) (Ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - DLG4 Antibody (C-term) (Rat) (Ascites) AM1833b
    Western blot analysis of RAT DLG4 Antibody (C-term) (Cat. #AM1833b) in mouse cerebellum tissue lysates (35μg/lane).DLG4 (arrow) was detected using the purified Mab.(1:100)
  • IHC-P - DLG4 Antibody (C-term) (Rat) (Ascites) AM1833b
    RAT DLG4 Antibody (C-term)(Ascites) (Cat. #AM1833b) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjμgation of the secondary antibody and DAB staining. This data demonstrates the use of the RAT DLG4 Antibody (C-term)(Ascites) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P31016
Other Accession Q62108, P78352
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 127CT15.8.20
Calculated MW 80465 Da
Antigen Region 677-706 aa
Additional Information
Gene ID 29495
Other Names Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 90, SAP-90, SAP90, Dlg4, Dlgh4, Psd95
Target/Specificity This DLG4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 677-706 amino acids from the C-terminal region of human DLG4.
Dilution WB~~1:100~500
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDLG4 Antibody (C-term) (Rat) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dlg4
Synonyms Dlgh4, Psd95 {ECO:0000303|PubMed:2775689
Function Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (By similarity).
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Cytoplasm. Cell projection, axon Note=High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells.
Tissue Location Expressed in brain (at protein level) (PubMed:12151521, PubMed:27307232). Detected in juxtaparanodal zones in the central nervous system and at nerve terminal plexuses of basket cells in the cerebellum (PubMed:20089912). Expressed in cerebrum (PubMed:27307232). Expressed in hippocampal neurons (at protein level) (PubMed:11502259, PubMed:12151521, PubMed:27307232, PubMed:27756895). Isoform 1 and isoform 2: highly expressed in cerebellum, cortex, hippocampus, and corpus striatum (PubMed:12151521).
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abcepta antibody to, and receive a free "I Love Antibodies" mug.


a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway [RGD]


SAP102 is a highly mobile MAGUK in spines. Zheng CY, et al. J Neurosci, 2010 Mar 31. PMID 20357126. Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation. de Arce KP, et al. J Neurosci, 2010 Mar 10. PMID 20220006. Transduced PDZ1 domain of PSD-95 decreases Src phosphorylation and increases nNOS (Ser847) phosphorylation contributing to neuroprotection after cerebral ischemia. Wang WW, et al. Brain Res, 2010 Apr 30. PMID 20197063. Hidden dynamic allostery in a PDZ domain. Petit CM, et al. Proc Natl Acad Sci U S A, 2009 Oct 27. PMID 19828436. Integrin-linked kinase is involved in cocaine sensitization by regulating PSD-95 and synapsin I expression and GluR1 Ser845 phosphorylation. Chen Q, et al. J Mol Neurosci, 2010 Mar. PMID 19629758.

Abcepta welcomes feedback from its customers.

If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 325.00
Cat# AM1833b
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abcepta, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions