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LHX2 Antibody
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P50458 |
| Other Accession | NP_004780.3 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgM,k |
| Clone/Animal Names | 285CT11.1.1 |
| Calculated MW | 44373 Da |
| Gene ID | 9355 |
|---|---|
| Other Names | LIM/homeobox protein Lhx2, Homeobox protein LH-2, LIM homeobox protein 2, LHX2, LH2 |
| Target/Specificity | This LHX2 monoclonal antibody is generated from mouse immunized with LHX2 recombinant protein. |
| Dilution | WB~~1:500~1000 E~~Use at an assay dependent concentration. |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LHX2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LHX2 |
|---|---|
| Synonyms | LH2 |
| Function | Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq].
References
Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)
Glenn, D.J., et al. J. Biol. Chem. 274(51):36159-36167(1999)
Bach, I., et al. Nat. Genet. 22(4):394-399(1999)
Rincon-Limas, D.E., et al. Proc. Natl. Acad. Sci. U.S.A. 96(5):2165-2170(1999)
Bendall, A.J., et al. Differentiation 63(3):151-157(1998)
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