|Application ||WB, E|
|Calculated MW||14858 Da|
|Other Names||Fatty acid-binding protein, heart, Fatty acid-binding protein 3, Heart-type fatty acid-binding protein, H-FABP, Mammary-derived growth inhibitor, MDGI, Muscle fatty acid-binding protein, M-FABP, FABP3, FABP11, MDGI|
|Target/Specificity||Purified His-tagged Cardiac FABP protein(Fragment) was used to produced this monoclonal antibody.|
|Format||Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Cardiac FABP Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.|
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The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. [provided by RefSeq].
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Jassim, G., et al. Pharmacopsychiatry (2010) In press : Boscheri, A., et al. Am. Heart J. 160(2):294-300(2010) Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
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