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CALCA/CT Antibody
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P01258 |
| Other Accession | NP_001732.1, NP_001029124.1 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgM |
| Clone/Animal Names | 406CT21.4.3 |
| Calculated MW | 15467 Da |
| Antigen Region | 56-84 aa |
| Gene ID | 796 |
|---|---|
| Other Names | Calcitonin, Calcitonin, Katacalcin, Calcitonin carboxyl-terminal peptide, CCP, PDN-21, CALCA, CALC1 |
| Target/Specificity | This CALCA/CT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from human CALCA/CT. |
| Dilution | WB~~1:500~1000 |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CALCA/CT Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CALCA |
|---|---|
| Synonyms | CALC1 |
| Function | Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
References
Giroux, S., et al. Bone 47(5):975-981(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Lee, J.Y., et al. Korean J Lab Med 30(4):406-413(2010)
Giovanella, L., et al. Clin. Chem. Lab. Med. 48(8):1163-1165(2010)
Hatzistilianou, M. ScientificWorldJournal 10, 1941-1946 (2010) :
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