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UBL5 Antibody(Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • WB - UBL5 Antibody(Ascites) AM2024a
    UBL5 Antibody (Cat. #AM2024a) western blot analysis in mouse heart tissue lysates (35μg/lane).This demonstrates the UBL5 antibody detected the UBL5 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9BZL1
Other Accession Q9EPV8, Q3T0Z3, NP_001041706.1, NP_077268.1
Reactivity Human, Mouse
Predicted Bovine
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone/Animal Names 429CT16.3.1
Calculated MW 8547 Da
Additional Information
Gene ID 59286
Other Names Ubiquitin-like protein 5, UBL5
Target/Specificity Purified His-tagged UBL5 protein was used to produced this monoclonal antibody.
Dilution WB~~1:500~8000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUBL5 Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBL5
Function Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins (PubMed:25092792). Participates thereby in pre- mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers (PubMed:25862789). Plays also a protective role against ER stress-induced apoptosis (PubMed:37315790).
Cellular Location Cytoplasm. Nucleus. Nucleus, Cajal body
Tissue Location Ubiquitous. Highest level of expression in heart, skeletal muscle, kidney, liver, iris and lymphoblasts
Research Areas
Citations (0)
citation

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Background

Ubiquitin-like proteins (UBLs) are thought to be reversible modulators of protein function rather than protein degraders like ubiquitin (MIM 191339).

References

de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Sentinelli, F., et al. J. Pediatr. Endocrinol. Metab. 21(12):1139-1145(2008)
Bozaoglu, K., et al. Hum. Biol. 78(2):147-159(2006)
Wilkinson, C.R., et al. Curr. Biol. 14(24):2283-2288(2004)
Jowett, J.B., et al. Diabetes 53(9):2467-2472(2004)

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$ 182.50
Cat# AM2024a
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