|Application ||WB, E|
|Calculated MW||38999 Da|
|Antigen Region||77-104 aa|
|Other Names||Protein AMBP, Alpha-1-microglobulin, Protein HC, Alpha-1 microglycoprotein, Complex-forming glycoprotein heterogeneous in charge, Inter-alpha-trypsin inhibitor light chain, ITI-LC, Bikunin, EDC1, HI-30, Uronic-acid-rich protein, Trypstatin, AMBP, HCP, ITIL|
|Target/Specificity||This AMBP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 77-104 amino acids from the N-terminal region of human AMBP.|
|Format||Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AMBP Antibody (N-term) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.|
|Tissue Location||Expressed by the liver and secreted in plasma. Alpha-1-microglobulin occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid. Inter-alpha- trypsin inhibitor is present in plasma and urine|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.
Olsson, M.G., et al. Radiat. Res. 174(5):590-600(2010)
Allhorn, M., et al. Blood 99(6):1894-1901(2002)
Amoresano, A., et al. Eur. J. Biochem. 267(7):2105-2112(2000)
Xu, Y., et al. J. Mol. Biol. 276(5):955-966(1998)
Vetr, H., et al. Biol. Chem. Hoppe-Seyler 371(12):1185-1196(1990)
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