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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Phospho Antibodies   >   Testicular Receptor 4 (TR4) Antibody   

Testicular Receptor 4 (TR4) Antibody

Rabbit polyclonal antibody

  • WB - Testicular Receptor 4 (TR4) Antibody AN1172
    Western blot of rat cerebellum lysate showing specific immunolabelingof the ~ 64k TR4 protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49117
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 64 KDa
Additional Information
Gene ID 22026
Gene Name NR2C2
Other Names Nuclear receptor subfamily 2 group C member 2, Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, Testicular receptor 4, Nr2c2, Mtr2r1, Tak1, Tr4
Target/Specificity Fusion protein from the N-terminal region of mouse TR4.
Dilution WB~~ 1:1000
Format neat serum
Antibody Specificity Specific for the ~64 kDa TR4 protein by Western blot in cerebellum and nuclear extracts from MEL cell lines.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTesticular Receptor 4 (TR4) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
ShippingBlue Ice
Research Areas
Citations (0)

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Testicular receptor 4 (TR4) is a member of the orphan nuclear receptor superfamily. Data suggests that TR4 may function as a regulator that modulates many signaling pathways. It has been suggested that TR4 is required for normal cerebellar development as TR4 knockout mice exhibit behavioral deficits in motor coordination (Chen, YT et al.,2008) and plays important roles in growth, embryonic and early postnatal survival (Collins, LL, et al., 2004).


Chen YT, Collins LL, Chang SS, Chang C (2008) The roles of testicular orphan nuclear receptor
4 (TR4) in cerebellar development. Cerebellum 7(1):9-17.
Collins LL, Lee YF, Heinlein CA, Liu NC, Chen YT, Shyr CR, Meshul CK, Uno H, Platt KA,
Chang C (2004) Growth retardation and abnormal maternal behavior in mice lacking testicular
orphan nuclear receptor 4. PNAS 101(42):15058-63
Tanabe O, Shen Y, Liu Q, Campbell AD, Kuroha T, Yamamoto M, Engel JD. “The TR2 and TR4
orphan nuclear receptors repress Gata1 transcription.” Genes Dev. 2007, 21:2832-2844.

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$ 310.00
Cat# AN1172
Availability: 7-10 days
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