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GYS1 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | P13807 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 3A7 |
| Isotype | IgG1 |
| Calculated MW | 85kDa |
| Description | Glycogen synthase, skeletal muscle, the rate limiting enzyme of the insulin-induced glycogenesis. The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1, 4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Muscle GS is expressed in several tissues. |
| Immunogen | Purified recombinant fragment of human GYS1 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Gene ID | 2997 |
|---|---|
| Other Names | Glycogen [starch] synthase, muscle, 2.4.1.11, GYS1, GYS |
| Dilution | E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GYS1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GYS1 (HGNC:4706) |
|---|---|
| Synonyms | GYS |
| Function | Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. |
| Tissue Location | Expressed in skeletal muscle and most other cell types where glycogen is present. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
1. PLoS One. 2007 Mar 14;2(3):e285. 2. Mol Syst Biol. 2007;3:89. Epub 2007 Mar 13.
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$ 385.00
Cat# AO1511a
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