NIPA4 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q0D2K0 |
| Other Accession | NP_001092757.1, NP_001165763.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 44005 Da |
| Antigen Region | 9-37 aa |
| Gene ID | 348938 |
|---|---|
| Other Names | Magnesium transporter NIPA4, Ichthyin, NIPA-like protein 4, Non-imprinted in Prader-Willi/Angelman syndrome region protein 4, NIPAL4, ICHN, NIPA4 |
| Target/Specificity | This NIPA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human NIPA4. |
| Dilution | IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NIPA4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NIPAL4 |
|---|---|
| Synonyms | ICHN, NIPA4 |
| Function | Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Ba(2+), Sr(2+) and Fe(2+) but to a much less extent than Mg(2+) (By similarity). May be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway (PubMed:15317751). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9JJC8}; Multi-pass membrane protein |
| Tissue Location | Highly expressed in brain, lung, stomach, keratinocytes and leukocytes, and in all other tissues tested except liver, thyroid and fetal brain. |

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