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CHPT1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | Q8WUD6 |
| Other Accession | Q8C025, Q1LZE6, Q8WUD6-2, NP_064629.2 |
| Reactivity | Human |
| Predicted | Bovine, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45097 Da |
| Antigen Region | 7-33 aa |
| Gene ID | 56994 |
|---|---|
| Other Names | Cholinephosphotransferase 1, hCPT1, AAPT1-like protein, Diacylglycerol cholinephosphotransferase 1, CHPT1, CPT1 |
| Target/Specificity | This CHPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-33 amino acids from the N-terminal region of human CHPT1. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CHPT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CHPT1 (HGNC:17852) |
|---|---|
| Synonyms | CPT1 |
| Function | Catalyzes the final step of de novo phosphatidylcholine (PC) synthesis, i.e. the transfer of choline phosphate from CDP-choline to the free hydroxyl of a diacylglycerol (DAG), producing a PC. It thereby plays a central role in the formation and maintenance of vesicular membranes. |
| Cellular Location | Golgi apparatus membrane; Multi-pass membrane protein |
| Tissue Location | Highly expressed in testis, colon, small intestine, heart, prostate and spleen. Also detected in kidney, skeletal muscle, pancreas, leukocytes, ovary and thymus. Weakly expressed in the brain, placenta and lung. Overexpressed in cancerous breast epithelial cell lines. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Akech, J., et al. Biochem. Biophys. Res. Commun. 333(1):35-41(2005)
Ghosh, A., et al. Biochem. Biophys. Res. Commun. 297(4):1043-1048(2002)
Henneberry, A.L., et al. J. Biol. Chem. 275(38):29808-29815(2000)
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