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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   KATL1 Antibody (N-term)   

KATL1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KATL1 Antibody  (N-term) AP10229a
    KATL1 Antibody (N-term) (Cat. #AP10229a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KATL1 antibody detected the KATL1 protein (arrow).
  • IHC-P - KATL1 Antibody  (N-term) AP10229a
    KATL1 antibody (N-term) (Cat. #AP10229a) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KATL1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - KATL1 Antibody  (N-term) AP10229a
    KATL1 Antibody (N-term) (Cat. #AP10229a) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BW62
Other Accession NP_115492.1, NP_001014402.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55392 Da
Antigen Region 137-166 aa
Additional Information
Gene ID 84056
Other Names Katanin p60 ATPase-containing subunit A-like 1 {ECO:0000255|HAMAP-Rule:MF_03024}, Katanin p60 subunit A-like 1 {ECO:0000255|HAMAP-Rule:MF_03024}, 3643 {ECO:0000255|HAMAP-Rule:MF_03024}, p60 katanin-like 1 {ECO:0000255|HAMAP-Rule:MF_03024}, KATNAL1 {ECO:0000255|HAMAP-Rule:MF_03024}
Target/Specificity This KATL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the N-terminal region of human KATL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKATL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KATNAL1 {ECO:0000255|HAMAP-Rule:MF_03024}
Function Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro (PubMed:26929214).
Cellular Location Cytoplasm, cytoskeleton {ECO:0000255|HAMAP- Rule:MF_03024, ECO:0000269|PubMed:22654668}. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with microtubules throughout the basal and adluminal compartments of Sertoli cells (By similarity). Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (PubMed:26929214). {ECO:0000250|UniProtKB:Q8K0T4, ECO:0000269|PubMed:26929214}
Tissue Location Expressed in testis, restricted to Sertoli cells (at protein level).
Research Areas
Citations (0)

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Dunham, A., et al. Nature 428(6982):522-528(2004)
Millar, J.K., et al. Biochem. Biophys. Res. Commun. 311(4):1019-1025(2003)
Robertson, N.G., et al. Genomics 23(1):42-50(1994)

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$ 325.00
$ 109.00
Cat# AP10229a
Availability: In Stock
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