- CITATIONS: 1
|Application ||IHC-P, WB, E|
|Other Accession||A1A5Q0, Q3UHZ5, NP_997046.1|
|Calculated MW||61675 Da|
|Antigen Region||60-88 aa|
|Other Names||Leiomodin-2, Cardiac leiomodin, C-LMOD, LMOD2|
|Target/Specificity||This LMOD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human LMOD2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LMOD2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates nucleation of actin filaments and thereby promotes actin polymerization (PubMed:18403713, PubMed:26370058, PubMed:25250574, PubMed:26417072). Plays a role in the regulation of actin filament length (By similarity). Required for normal sarcomere organization in the heart, and for normal heart function (PubMed:18403713).|
|Cellular Location||Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, M line Cytoplasm, cytoskeleton Note=Colocalizes with actin filaments in sarcomeres. Detected close to the M line.|
|Tissue Location||Specifically expressed in heart and skeletal muscles, with higher levels in heart (at protein level). Not expressed in other tissues.|
Provided below are standard protocols that you may find useful for product applications.
Chereau, D., et al. Science 320(5873):239-243(2008)
Lane, H.Y., et al. J Clin Psychopharmacol 26(2):128-134(2006)
Conley, C.A., et al. Genomics 73(2):127-139(2001)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.