MRM1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
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Primary Accession | Q6IN84 |
Other Accession | NP_079140.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 38638 Da |
Antigen Region | 80-109 aa |
Gene ID | 79922 |
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Other Names | rRNA methyltransferase 1, mitochondrial, 211-, 16S rRNA (guanosine(1145)-2'-O)-methyltransferase, 16S rRNA [Gm1145] 2'-O-methyltransferase, MRM1 {ECO:0000303|PubMed:24036117} |
Target/Specificity | This MRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the N-terminal region of human MRM1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MRM1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MRM1 {ECO:0000303|PubMed:24036117} |
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Function | S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. |
Cellular Location | Mitochondrion matrix |
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Provided below are standard protocols that you may find useful for product applications.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
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