|Application ||WB, E|
|Other Accession||Q9Z137, P59270, NP_542780.1|
|Calculated MW||36919 Da|
|Antigen Region||123-150 aa|
|Other Names||Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2, Beta-1, 3-glucuronyltransferase 2, GlcAT-D, UDP-glucuronosyltransferase S, GlcAT-S, Glucuronosyltransferase S, B3GAT2, GLCATS, KIAA1963|
|Target/Specificity||This B3GAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-150 amino acids from the Central region of human B3GAT2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||B3GAT2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in the trachea, retina, spinal cord, hippocampus and other brain regions, and, at lower levels, in testis and ovary|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system. [provided by RefSeq].
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Shiba, T., et al. Proteins 65(2):499-508(2006)
Kakuda, S., et al. Glycobiology 15(2):203-210(2005)
Kakuda, S., et al. Protein Expr. Purif. 35(1):111-119(2004)
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