Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
CHIC2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UKJ5 |
| Other Accession | Q9D9G3, NP_036242.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 19254 Da |
| Antigen Region | 138-165 aa |
| Gene ID | 26511 |
|---|---|
| Other Names | Cysteine-rich hydrophobic domain-containing protein 2, BrX-like translocated in leukemia, CHIC2, BTL |
| Target/Specificity | This CHIC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-165 amino acids from the C-terminal region of human CHIC2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CHIC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CHIC2 |
|---|---|
| Synonyms | BTL |
| Cellular Location | Cell membrane. Cytoplasmic vesicle. Note=Also present at a Golgi-like vesicular compartment and at scattered vesicles |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
CHIC2 is a member of the CHIC family of proteins. This protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane.
References
Fink, S.R., et al. Leuk. Res. 33(6):843-846(2009)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Pardanani, A., et al. Blood 102(9):3093-3096(2003)
Cools, J., et al. FEBS Lett. 492(3):204-209(2001)
Cools, J., et al. FEBS Lett. 492(3):204-209(2001)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
