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DEN5A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q6IQ26 |
| Other Accession | Q6PAL8, NP_056028.2, G3V7Q0 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 147096 Da |
| Antigen Region | 695-724 aa |
| Gene ID | 23258 |
|---|---|
| Other Names | DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1, DENND5A, KIAA1091, RAB6IP1 |
| Target/Specificity | This DEN5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 695-724 amino acids from the Central region of human DEN5A. |
| Dilution | FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DEN5A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DENND5A |
|---|---|
| Synonyms | KIAA1091, RAB6IP1 |
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth (By similarity). |
| Cellular Location | Golgi apparatus membrane {ECO:0000250|UniProtKB:Q6PAL8} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in Rab6-mediated GTPase signaling.
References
Recacha, R., et al. Structure 17(1):21-30(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Janoueix-Lerosey, I., et al. J. Biol. Chem. 270(24):14801-14808(1995)
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