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KIAA1609 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, IHC-P, E |
|---|---|
| Primary Accession | Q6P9B6 |
| Other Accession | NP_065998.3 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50994 Da |
| Antigen Region | 426-456 aa |
| Gene ID | 57707 |
|---|---|
| Other Names | TLD domain-containing protein 1, TBC/LysM-associated domain-containing protein 1, TLDC1, KIAA1609 |
| Target/Specificity | This KIAA1609 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-456 amino acids from the C-terminal region of human K1609. |
| Dilution | FC~~1:10~50 WB~~1:8000 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KIAA1609 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MEAK7 (HGNC:29325) |
|---|---|
| Synonyms | KIAA1609, TLDC1 |
| Function | Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration (PubMed:29750193). Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome (PubMed:29750193). |
| Cellular Location | Membrane. Cytoplasm. Lysosome |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Rothenberg, M.E., et al. Nat. Genet. 42(4):289-291(2010)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
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