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MYCT1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q8N699 |
| Other Accession | NP_079383.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26593 Da |
| Antigen Region | 135-163 aa |
| Gene ID | 80177 |
|---|---|
| Other Names | Myc target protein 1, Myc target in myeloid cells protein 1, MYCT1, MTLC, MTMC1 |
| Target/Specificity | This MYCT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-163 amino acids from the C-terminal region of human MYCT1. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MYCT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MYCT1 |
|---|---|
| Synonyms | MTLC, MTMC1 |
| Function | May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity). |
| Cellular Location | Nucleus. Note=Expressed in nuclei of hepatocellular carcinoma cell line BEL-7402 cells |
| Tissue Location | Down-regulated in gastric cancer tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).
References
Qiu, G.B., et al. World J. Gastroenterol. 9(10):2160-2163(2003)
Qiu, G., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20(2):94-97(2003)
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