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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   LRRC57 Antibody (C-term)   

LRRC57 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LRRC57 Antibody (C-term) AP10537B
    LRRC57 Antibody (C-term) (Cat. #AP10537b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the LRRC57 antibody detected the LRRC57 protein (arrow).
  • IHC-P - LRRC57 Antibody (C-term) AP10537B
    LRRC57 Antibody (C-term) (Cat. #AP10537b) immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LRRC57 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - LRRC57 Antibody (C-term) AP10537B
    LRRC57 Antibody (C-term) (Cat. #AP10537b) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession Q8N9N7
Other Accession Q5FVI3, NP_694992.2
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 198-227 aa
Additional Information
Other Names Leucine-rich repeat-containing protein 57, LRRC57
Target/Specificity This LRRC57 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the C-terminal region of human LRRC57.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLRRC57 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LRRC57
Cellular Location Membrane; Lipid-anchor EMBL; AK094131; BAC04294.1; -; mRNA EMBL; AK094891; BAC04451.1; -; mRNA EMBL; CR749223; CAH18079.1; -; mRNA EMBL; BX538324; CAD98097.1; -; mRNA EMBL; BC058935; AAH58935.1; -; mRNA CCDS; CCDS10089.1; - RefSeq; NP_694992.2; NM_153260.2 UniGene; Hs.234681; - ProteinModelPortal; Q8N9N7; - SMR; Q8N9N7; - BioGrid; 129089; 7 IntAct; Q8N9N7; 1 STRING; 9606.ENSP00000326817; - iPTMnet; Q8N9N7; - PhosphoSitePlus; Q8N9N7; - BioMuta; LRRC57; - DMDM; 74760039; - EPD; Q8N9N7; - jPOST; Q8N9N7; - MaxQB; Q8N9N7; - PaxDb; Q8N9N7; - PeptideAtlas; Q8N9N7; - PRIDE; Q8N9N7; - ProteomicsDB; 72569; - DNASU; 255252; - Ensembl; ENST00000323443; ENSP00000326817; ENSG00000180979 Ensembl; ENST00000397130; ENSP00000380319; ENSG00000180979 Ensembl; ENST00000563454; ENSP00000455445; ENSG00000180979 GeneID; 255252; - KEGG; hsa:255252; - UCSC; uc001zqc.4; human CTD; 255252; - EuPathDB; HostDB:ENSG00000180979.9; - GeneCards; LRRC57; - HGNC; HGNC:26719; LRRC57 HPA; HPA040894; - neXtProt; NX_Q8N9N7; - OpenTargets; ENSG00000180979; - PharmGKB; PA142671516; - eggNOG; KOG0619; Eukaryota eggNOG; COG4886; LUCA GeneTree; ENSGT00940000157393; - HOGENOM; HOG000116557; - HOVERGEN; HBG054710; - InParanoid; Q8N9N7; - OMA; FEMKQFA; - OrthoDB; 1348484at2759; - PhylomeDB; Q8N9N7; - TreeFam; TF326481; - ChiTaRS; LRRC57; human GeneWiki; LRRC57; - GenomeRNAi; 255252; - PRO; PR:Q8N9N7; - Proteomes; UP000005640; Chromosome 15 Bgee; ENSG00000180979; Expressed in 194 organ(s), highest expression level in amniotic fluid ExpressionAtlas; Q8N9N7; baseline and differential Genevisible; Q8N9N7; HS GO; GO:0070062; C:extracellular exosome; HDA:UniProtKB GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell Gene3D; 3.80.10.10; -; 2 InterPro; IPR001611; Leu-rich_rpt InterPro; IPR003591; Leu-rich_rpt_typical-subtyp InterPro; IPR032675; LRR_dom_sf Pfam; PF00560; LRR_1; 1 Pfam; PF13855; LRR_8; 2 SMART; SM00369; LRR_TYP; 5 PROSITE; PS51450; LRR; 7 1: Evidence at protein level; Complete proteome; Leucine-rich repeat; Lipoprotein; Membrane; Myristate; Reference proteome; Repeat INIT_MET 1 1 Removed. CHAIN 2 239 Leucine-rich repeat-containing protein 57 /FTId=PRO_0000227778 REPEAT 39 60 LRR 1 REPEAT 63 84 LRR 2 REPEAT 86 107 LRR 3 REPEAT 109 131 LRR 4 REPEAT 132 153 LRR 5 REPEAT 154 175 LRR 6 REPEAT 177 197 LRR 7 REPEAT 202 222 LRR 8 LIPID 2 2 N-myristoyl glycine CONFLICT 71 71 N -> S (in Ref. 2; CAD98097) CONFLICT 237 237 K -> N (in Ref. 1; BAC04451) SEQUENCE 239 AA; 26754 MW; 8CA6E06075D10E3D CRC64; MGNSALRAHV ETAQKTGVFQ LKDRGLTEFP ADLQKLTSNL RTIDLSNNKI ESLPPLLIGK FTLLKSLSLN NNKLTVLPDE ICNLKKLETL SLNNNHLREL PSTFGQLSAL KTLSLSGNQL GALPPQLCSL RHLDVMDLSK NQIRSIPDSV GELQVIELNL NQNQISQISV KISCCPRLKI LRLEENCLEL SMLPQSILSD SQICLLAVEG NLFEIKKLRE LEGYDKYMER FTATKKKFA
Research Areas
Citations (0)

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Background

LRRC57 contains 7 LRR (leucine rich repeats). However, the exact function remains unknown.

References

Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 325.00
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Cat# AP10537B
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