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WDR49 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q8IV35 |
| Other Accession | NP_849146.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 119003 Da |
| Antigen Region | 550-579 aa |
| Other Names | WD repeat-containing protein 49, WDR49 |
|---|---|
| Target/Specificity | This WDR49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 550-579 amino acids from the C-terminal region of human WDR49. |
| Dilution | FC~~1:10~50 IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | WDR49 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CFAP337 {ECO:0000305} |
|---|---|
| Synonyms | WDR49 {ECO:0000312|HGNC:HGNC:26587} |
| Function | Associates with components of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility, and might act as an inner dynein arm (IDA) hub or linkage. |
| Cellular Location | Cell projection, cilium {ECO:0000250|UniProtKB:I7MM07} |
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Provided below are standard protocols that you may find useful for product applications.
Background
WDR49 contains 8 WD repeats. The exact function of WDR49 remains unknown. There are two named isoforms.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
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