HPSE Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | E9PFG6 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 10338 Da |
Antigen Region | 26-54 aa |
Other Names | Heparanase |
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Target/Specificity | This HPSE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the Central region of human HPSE. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HPSE Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HPSE {ECO:0000313|EMBL:CAF28887.1} |
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Cellular Location | Secreted {ECO:0000256|ARBA:ARBA00004613}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.
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