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ATP1A4 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | Q13733 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 114166 Da |
| Antigen Region | 12-46 aa |
| Gene ID | 480 |
|---|---|
| Other Names | Sodium/potassium-transporting ATPase subunit alpha-4, Na(+)/K(+) ATPase alpha-4 subunit, 3.6.3.9, Sodium pump subunit alpha-4, ATP1A4, ATP1AL2 |
| Target/Specificity | This ATP1A4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-46 amino acids from the human region of human ATP1A4. |
| Dilution | WB~~1:2000 FC~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ATP1A4 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ATP1A4 (HGNC:14073) |
|---|---|
| Synonyms | ATP1AL2 |
| Function | This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Note=In mature sperm, located in the principle piece of the sperm flagellum |
| Tissue Location | Specifically expressed in testis. Found in very low levels in skeletal muscle. Expressed in mature sperm (at protein level) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility.
References
Hlivko J.T.,et al.Mol. Reprod. Dev. 73:101-115(2006).
Gregory S.G.,et al.Nature 441:315-321(2006).
Keryanov S.,et al.Gene 292:151-166(2002).
Shamraj O.I.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:12952-12956(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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