HMX2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P43687 |
Other Accession | Q8JJ64, P42581, A6NHT5, Q504H8, O57601, A2RU54, NP_666110 |
Reactivity | Mouse |
Predicted | Human, Chicken, Zebrafish, Xenopus |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 29634 Da |
Antigen Region | 149-180 aa |
Gene ID | 15372 |
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Other Names | Homeobox protein HMX2, Homeobox protein Nkx-52, Hmx2, Nkx-52, Nkx5-2 |
Target/Specificity | This HMX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-180 amino acids of mouse HMX2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HMX2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Hmx2 |
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Synonyms | Nkx-5.2, Nkx5-2 |
Function | Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in the developing CNS, including a specific expression in vestibular structures throughout inner ear development. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Homeobox genes represent a class of transcription factors that play key roles in the regulation of embryogenesis and development. Here we report the identification of a homeobox-containing gene family that is highly conserved at both the nucleotide and amino acid levels in a diverse number of species. These species encompass both vertebrate and invertebrate phylogenies, ranging from Homo sapiens to Drosophila melanogaster.
References
Wang,W., Dev. Cell 7 (3), 439-453 (2004)
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