DNM3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q9UQ16 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 97746 Da |
Antigen Region | 557-584 aa |
Gene ID | 26052 |
---|---|
Other Names | Dynamin-3, Dynamin, testicular, T-dynamin, DNM3, KIAA0820 |
Target/Specificity | This DNM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-584 amino acids from the Central region of human DNM3. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DNM3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DNM3 |
---|---|
Synonyms | KIAA0820 |
Function | Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity). |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the dynamin family, such as DNM3, possess mechanochemical properties involved in actin-membrane processes, predominantly in membrane budding.
References
Orth,J.D. et.al., Curr. Opin. Cell Biol. 15 (1), 31-39 (2003)
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