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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FMOD Antibody (C-term)   

FMOD Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FMOD Antibody (C-term) AP9243b
    Western blot analysis of FMOD Antibody (C-term) (Cat. #AP9243b) in mouse cerebellum tissue lysates (35ug/lane). FMOD (arrow) was detected using the purified Pab.
    detail
  • IHC-P - FMOD Antibody (C-term) AP9243b
    Formalin-fixed and paraffin-embedded human brain tissue reacted with FMOD Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
  • FC - FMOD Antibody (C-term) AP9243b
    FMOD Antibody (C-term) (Cat. #AP9243b) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession Q06828
Other Accession P13605
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 43179 Da
Antigen Region 337-364 aa
Additional Information
Gene ID 2331
Other Names Fibromodulin, FM, Collagen-binding 59 kDa protein, Keratan sulfate proteoglycan fibromodulin, KSPG fibromodulin, FMOD, FM, SLRR2E
Target/Specificity This FMOD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-364 amino acids from the C-terminal region of human FMOD.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFMOD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FMOD
Synonyms FM, SLRR2E
Function Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix
Research Areas
Citations (0)
citation

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Background

Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.

References

Ehret,G.B., et.al, Eur. J. Hum. Genet. 17 (12), 1650-1657 (2009)
Tillgren,V., et.al, J. Biol. Chem. 284 (42), 28543-28553 (2009)

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$ 365.00
$ 140.00
Cat# AP9243b
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