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IL2RG Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession P31785
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 42287 Da
Antigen Region 200-229 aa
Additional Information
Gene ID 3561
Other Names Cytokine receptor common subunit gamma, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132, IL2RG
Target/Specificity This IL2RG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-229 amino acids from the Central region of human IL2RG.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL2RG Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL2RG
Function Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770).
Cellular Location Cell membrane; Single-pass type I membrane protein. Cell surface
Research Areas
Citations (0)
citation

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Background

IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain.

References

Ross, J.A., et al. J. Biol. Chem. 285(6):3582-3591(2010)
Ameratunga, R., et al. N. Z. Med. J. 122(1304):46-53(2009)
Clark, P.A., et al. Hum. Genet. 96(4):427-432(1995)
Ohbo, K., et al. J. Biol. Chem. 270(13):7479-7486(1995)
Bamborough, P., et al. Structure 2(9):839-851(1994)

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Discontinued
Cat# AP9450c
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