|Application ||WB, ICC/IF|
|Description||Rabbit Anti-Human Beclin 2 Polyclonal|
|Target/Specificity||Detects ~48 kDa.|
|Other Names||BECN1P1 Antibody, Beclin-1 autophagy-related pseudogene 1 Antibody, BECN2 Antibody, Beclin-2 Antibody, BECN1L1 Antibody, Beclin-1-like protein 1 Antibody,|
|Immunogen||Synthetic peptide from the C-terminal of Human Beclin 2 (aa. 338-349)|
|Purification||Peptide Affinity Purified|
|Storage Buffer||PBS, 50% glycerol, 0.09% sodium azide|
|Shipping Temperature||Blue Ice or 4ºC|
|Certificate of Analysis||A 1:1000 dilution of SPC-603 was sufficient for detection of Beclin 2 in 15 µg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.|
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Provided below are standard protocols that you may find useful for product applications.
Beclin 2 is a novel coiled-coil protein related to the autophagic Beclin 1 protein. It is thought to interact with Bcl-2, an anti-apoptotic protein, and is believed to function in autophagy. It has alson been found to mediate G protein-coupled receptro (GPCR) degradation (1).
1. He C., et al. (2013) Cell. 154(5): 1085-1099.
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