Beclin 2 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC |
---|---|
Primary Accession | P0DM65 |
Other Accession | NP_001277621.1 |
Host | Rabbit |
Reactivity | Human, Mouse |
Clonality | Polyclonal |
Description | Rabbit Anti-Mouse Beclin 2 Polyclonal |
Target/Specificity | Detects ~48 kDa. |
Other Names | Becn2 Antibody, Beclin-2 Antibody, PFM 2 Antibody, Antibody, PR domain zinc finger protein 5 Antibody, Antibody, PRDM 5 Antibody, Antibody, PRDM5 protein Antibody, Antibody, PR domain-containing protein 5 Antibody, Antibody, PRDM5 Antibody, Antibody, PFM2 Antibody, Antibody, PR domain containing 5 Antibody, Antibody, PRDM5_HUMAN Antibody, Antibody, PR domain containing protein 5 Antibody, Antibody, BCS2 Antibody, Antibody, |
Immunogen | Synthetic peptide from the C-terminal of Mouse Beclin 2 (aa. 410-421) |
Purification | Peptide Affinity Purified |
Storage | -20ºC |
Storage Buffer | PBS, 50% glycerol, 0.09% sodium azide |
Shipping Temperature | Blue Ice or 4ºC |
Certificate of Analysis | A 1:1000 dilution of SPC-604 was sufficient for detection of Beclin 2 in 15 µg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. |
Cellular Localization | Cytoplasm |
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Provided below are standard protocols that you may find useful for product applications.
Background
Beclin 2 is a novel coiled-coil protein related to the autophagic Beclin 1 protein. It is thought to interact with Bcl-2, an anti-apoptotic protein, and is believed to function in autophagy. It has alson been found to mediate G protein-coupled receptro (GPCR) degradation (1).
References
1. He C., et al. (2013) Cell. 154(5): 1085-1099.
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