|Application ||WB, ICC/IF|
|Description||Rabbit Anti-Human BDNF Polyclonal|
|Target/Specificity||Predicted molecular weight at ~27.9kDa.|
|Other Names||Abrineurin Antibody, ANON2 Antibody, BDNF_Human Antibody, Brain Derived Neurotrophic Factor Antibody, MGC34632 Antibody|
|Immunogen||Synthetic peptide from the N-terminal of human BDNF|
|Purification||Peptide Affinity Purified|
|Storage Buffer||PBS, 50% glycerol, 0.09% sodium azide|
|Shipping Temperature||Blue Ice or 4ºC|
|Certificate of Analysis||A 1:1000 dilution of SPC-703 was sufficient for detection of BDNF on 293T Rapamycin-treated lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.|
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Provided below are standard protocols that you may find useful for product applications.
Brain-derived neurotrophic factor, also known as BDNF, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical Nerve Growth Factor. Neurotrophic factors are found in the brain and the periphery. The effects of BDNF on motor neurons might be useful in treating patients with motor neuropathies and ALS (1-3).
1. Wetmore C., Ernfors P., Persson H., Olson L. (1990) Exp. Neurol. 109(2): 141-152.
2. Thoenen H., Zafra F., Hengerer B., Lindholm D. (1991) Ann NY Acad Sci. 640: 86-90.
3. Chun H.S., Son J.J., Son J.H. (2000) Neuroreport. 11(3): 511-514.
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