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AGTRAP Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant AGTRAP.

     
  • WB - AGTRAP Antibody (monoclonal) (M02) AT1069a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.46 KDa) .
    detail
  • WB - AGTRAP Antibody (monoclonal) (M02) AT1069a
    AGTRAP monoclonal antibody (M02), clone 1G2 Western Blot analysis of AGTRAP expression in Hela S3 NE ( (Cat # AT1069a )
    detail
  • WB - AGTRAP Antibody (monoclonal) (M02) AT1069a
    Western Blot analysis of AGTRAP expression in transfected 293T cell line by AGTRAP monoclonal antibody (M02), clone 1G2.

    Lane 1: AGTRAP transfected lysate(16.7 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • WB - AGTRAP Antibody (monoclonal) (M02) AT1069a
    Western blot analysis of AGTRAP over-expressed 293 cell line, cotransfected with AGTRAP Validated Chimera RNAi ( (Cat # AT1069a )
    detail
  • IHC - AGTRAP Antibody (monoclonal) (M02) AT1069a
    Immunoperoxidase of monoclonal antibody to AGTRAP on formalin-fixed paraffin-embedded human prostate. [antibody concentration 0.8 ug/ml]
    detail
  • E - AGTRAP Antibody (monoclonal) (M02) AT1069a
    Detection limit for recombinant GST tagged AGTRAP is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession Q6RW13
Other Accession NM_020350
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1G2
Calculated MW 17419 Da
Additional Information
Gene ID 57085
Other Names Type-1 angiotensin II receptor-associated protein, AT1 receptor-associated protein, AGTRAP, ATRAP
Target/Specificity AGTRAP (NP_065083, 108 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsAGTRAP Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.

References

Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.The small GTPase Ral couples the angiotensin II type 1 receptor to the activation of phospholipase C-delta 1. Godin CM, et al. Mol Pharmacol, 2010 Mar. PMID 20018811.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Influence of endogenous angiotensin II on control of sympathetic nerve activity in human dehydration. Rabbitts JA, et al. J Physiol, 2009 Nov 15. PMID 19805740.Genome-wide association study identifies eight loci associated with blood pressure. Newton-Cheh C, et al. Nat Genet, 2009 Jun. PMID 19430483.

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$ 350.00
Cat# AT1069a
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Availability: 7-10 days
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