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ALG12 Antibody (monoclonal) (M06)

Mouse monoclonal antibody raised against a partial recombinant ALG12.

     
  • WB - ALG12 Antibody (monoclonal) (M06) AT1120a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.01 KDa) .
    detail
  • WB - ALG12 Antibody (monoclonal) (M06) AT1120a
    ALG12 monoclonal antibody (M06), clone 5E3 Western Blot analysis of ALG12 expression in HeLa ( (Cat # AT1120a )
    detail
  • WB - ALG12 Antibody (monoclonal) (M06) AT1120a
    ALG12 monoclonal antibody (M06), clone 5E3. Western Blot analysis of ALG12 expression in PC-12 ( (Cat # AT1120a )
    detail
  • E - ALG12 Antibody (monoclonal) (M06) AT1120a
    Detection limit for recombinant GST tagged ALG12 is approximately 0.3ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9BV10
Other Accession NM_024105
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 5E4
Calculated MW 54655 Da
Additional Information
Gene ID 79087
Other Names Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1, 6-mannosyltransferase, Asparagine-linked glycosylation protein 12 homolog, hALG12, Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1, 6-mannosyltransferase, Mannosyltransferase ALG12 homolog, Membrane protein SB87, ALG12
Target/Specificity ALG12 (NP_077010, 369 a.a. ~ 425 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsALG12 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
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Background

This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation.

References

Large-scale cDNA transfection screening for genes related to cancer development and progression. Wan D, et al. Proc Natl Acad Sci U S A, 2004 Nov 2. PMID 15498874.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.A genome annotation-driven approach to cloning the human ORFeome. Collins JE, et al. Genome Biol, 2004. PMID 15461802.Congenital disorders of glycosylation: a booming chapter of pediatrics. Jaeken J, et al. Curr Opin Pediatr, 2004 Aug. PMID 15273506.Congenital disorders of glycosylation (CDG): update and new developments. Jaeken J. J Inherit Metab Dis, 2004. PMID 15272470.

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$ 350.00
Cat# AT1120a
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Availability: 7-10 days
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