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CAP1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant CAP1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q01518 |
| Other Accession | BC013963 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 4A2 |
| Calculated MW | 51901 Da |
| Gene ID | 10487 |
|---|---|
| Other Names | Adenylyl cyclase-associated protein 1, CAP 1, CAP1, CAP |
| Target/Specificity | CAP1 (AAH13963, 1 a.a. ~ 475 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | CAP1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified.
References
1.Expression and function of neuronal growth-associated proteins (nGAPs) in PC12 cells.Lu J, Nozumi M, Takeuchi K, Abe H, Igarashi M.Neurosci Res. 2011 Jan 14. [Epub ahead of print]2.Adenylyl cyclase-associated protein-1/CAP1 as a biological target substrate of gelatinase B/MMP-9.Cauwe B, Martens E, Van den Steen PE, Proost P, Van Aelst I, Blockmans D, Opdenakker G.Exp Cell Res. 2008 Sep 10;314(15):2739-49. Epub 2008 Jul 16.
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