CDC37L1 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full-length recombinant CDC37L1.
|Application ||WB, E|
|Calculated MW||38835 Da|
|Other Names||Hsp90 co-chaperone Cdc37-like 1, Hsp90-associating relative of Cdc37, CDC37L1, CDC37B, HARC|
|Target/Specificity||CDC37L1 (AAH14133, 1 a.a. ~ 337 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||CDC37L1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 [PubMed 11413142]).
Importance of the C-terminal domain of Harc for binding to Hsp70 and Hop as well as its response to heat shock. Cartledge K, et al. Biochemistry, 2007 Dec 25. PMID 18052042.Domain-mediated dimerization of the Hsp90 cochaperones Harc and Cdc37. Roiniotis J, et al. Biochemistry, 2005 May 3. PMID 15850399.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.Identification and characterization of Harc, a novel Hsp90-associating relative of Cdc37. Scholz GM, et al. J Biol Chem, 2001 Aug 17. PMID 11413142.Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. Suzuki Y, et al. Gene, 1997 Oct 24. PMID 9373149.
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