CETN1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant CETN1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q12798 |
Other Accession | BC029515 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG1 Kappa |
Clone Names | 2A6 |
Calculated MW | 19570 Da |
Gene ID | 1068 |
---|---|
Other Names | Centrin-1, Caltractin isoform 2, CETN1, CEN1, CETN |
Target/Specificity | CETN1 (AAH29515, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | CETN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.
References
Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability. Tsang WY, et al. Mol Biol Cell, 2006 Aug. PMID 16760425.The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Zhao ZS, et al. Mol Cell, 2005 Oct 28. PMID 16246726.HIV-1 Gag-RNA interaction occurs at a perinuclear/centrosomal site; analysis by confocal microscopy and FRET. Poole E, et al. Traffic, 2005 Sep. PMID 16101678.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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