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CNR2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CNR2.

     
  • IF - CNR2 Antibody (monoclonal) (M01) AT1575a
    Immunofluorescence of monoclonal antibody to CNR2 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • WB - CNR2 Antibody (monoclonal) (M01) AT1575a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.12 KDa) .
    detail
  • WB - CNR2 Antibody (monoclonal) (M01) AT1575a
    Western Blot analysis of CNR2 expression in transfected 293T cell line by CNR2 monoclonal antibody (M01), clone 3C7.

    Lane 1: CNR2 transfected lysate(39.7 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • E - CNR2 Antibody (monoclonal) (M01) AT1575a
    Detection limit for recombinant GST tagged CNR2 is 0.1 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession P34972
Other Accession NM_001841.1
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 3C7
Calculated MW 39681 Da
Additional Information
Gene ID 1269
Other Names Cannabinoid receptor 2, CB-2, CB2, hCB2, CX5, CNR2, CB2A, CB2B
Target/Specificity CNR2 (NP_001832.1, 302 a.a. ~ 360 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCNR2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

References

1.Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity.Brocato B, Zoerner AA, Janjetovic Z, Skobowiat C, Gupta S, Moore Ii BM, Slominski A, Zhang J, Schenone M, Phinehas R, Ferry RJ Jr, Dick E Jr, Hubbard GB, Mari G, Schlabritz-Loutsevitch NPlacenta. 2013 Sep 2. pii: S0143-4004(13)00692-9. doi: 10.1016/j.placenta.2013.08.007.

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$ 350.00
Cat# AT1575a
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Availability: 7-10 days
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