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CXCL5 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a full length recombinant CXCL5.

     
  • WB - CXCL5 Antibody (monoclonal) (M03) AT1693a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (38.28 KDa) .
    detail
  • WB - CXCL5 Antibody (monoclonal) (M03) AT1693a
    Western Blot analysis of CXCL5 expression in transfected 293T cell line by CXCL5 monoclonal antibody (M03), clone M1.

    Lane 1: CXCL5 transfected lysate(12 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • E - CXCL5 Antibody (monoclonal) (M03) AT1693a
    Detection limit for recombinant GST tagged CXCL5 is approximately 1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P42830
Other Accession BC008376
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 lambda
Clone Names M1
Calculated MW 11972 Da
Additional Information
Gene ID 6374
Other Names C-X-C motif chemokine 5, ENA-78(1-78), Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, Small-inducible cytokine B5, ENA-78(8-78), ENA-78(9-78), CXCL5, ENA78, SCYB5
Target/Specificity CXCL5 (AAH08376, 1 a.a. ~ 114 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCXCL5 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation.

References

Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Schuurhof A, et al. Pediatr Pulmonol, 2010 Jun. PMID 20503287.Elevated serum chemokine CXC ligand 5 levels are associated with hypercholesterolemia but not a worsening of insulin resistance in Chinese people. Yang Z, et al. J Clin Endocrinol Metab, 2010 Aug. PMID 20501684.[Association of ENA-78, IP-10 and VEGF gene polymorphism with idiopathic pulmonary fibrosis] Liu L, et al. Zhonghua Yi Xue Za Zhi, 2009 Oct 20. PMID 20137269.The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells. Thobe MN, et al. Oncogene, 2010 Jan 14. PMID 19838218.CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer. Okayama H, et al. Oncol Rep, 2009 Oct. PMID 19724852.

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$ 350.00
Cat# AT1693a
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Availability: 7-10 days
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